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    Biological Approaches to Spinal Disc Repair and Regeneration for Clinicians

    ISBN: 9781626232501
    AuthorHartl, Roger
    SubAuthor1Bonassar, Larry
    Pub Date03/08/2017
    AvailabilityCurrently out of stock. If available, delivery is usually 5-10 working days.
    Availability: Out of Stock

    Top Experts Share Clinical Insights on Biological Interventions for Spine-Related Disease

    Although there have been significant advancements in minimally invasive spinal surgery techniques in the last few decades, optimal outcomes for chronic low back pain remain elusive. A number of promising clinical trials have been conducted using tissue engineering and biological interventions for disc degeneration. Written by renowned innovators, this is the first book that covers implementation of these groundbreaking approaches for disc disease.

    The text begins with key fundamentals including anatomy and physiology, pathophysiology, imaging and biomechanics to delineate healthy versus diseased spine. Subsequent sections discuss treatment strategies, research findings, and future developments. Throughout each chapter, renowned spine surgeons and scientists share clinical pearls gleaned from hands-on experience.

    Key Highlights

    The current state of the art in biological and tissue engineering procedures for spinal disorders
    Treatment methodologies including nucleus replacement and repair, annulus fibrosus repair, total disc transplantation, and mechanical total disc replacement
    Innovative treatment strategies for disc regeneration, such as genes and proteins
    Growth factors including platelet-rich plasma (PRP), which has shown promise for the stimulation and acceleration of bone and soft tissue healing
    Cell-based therapy for spinal disc regeneration and repair including the use of stem cells and chondrocytes
    In-depth discussion of research including animal versus human model, in-vitro, and a summary of biologic clinical trials

    This is a must-have resource for trainee and practicing orthopaedic surgeons and neurosurgeons who treat patients for spine-related conditions. It is essential reading for all clinicians who have an interest in cutting-edge tissue engineering and biological treatment interventions.