Most of the methods in this text apply to all regression models, but special emphasis is given to multiple regression using generalised least squares for longitudinal data, the binary logistic model, models for ordinal responses, parametric survival regression models and the Cox semi parametric survival model.
This practical guide is designed for students and researchers with an existing knowledge of R who wish to learn how to apply it in an epidemiological context and exploit its versatility. It also serves as a broader introduction to the quantitative aspects of modern practical epidemiology.
This practical guide is designed for students and researchers with an existing knowledge of R who wish to learn how to apply it in an epidemiological context and exploit its versatility. It also serves as a broader introduction to the quantitative aspects of modern practical epidemiology.
Treats the topics of multiple comparisons, simultaneous and selective inference from avariety of different perspectives. The need for a systematic treatment of the eld originates from the relevanceof multiple comparisons in many applications (medicine, industry, economics), and from the diversityof approaches and developments.
This book concerns use of real world data (RWD) and real world evidence (RWE) to aid drug development across product cycle. RWD are healthcare data that are collected outside the constraints of conventual controlled randomized trials (CRTs); whereas RWE is the knowledge derived from aggregation and analysis of RWD.
In biostatistical research and courses, practitioners and students often lack a thorough understanding of how to apply statistical methods to synthesize biomedical and clinical trial data. Filling this knowledge gap, this book shows how to implement statistical meta-analysis methods to real data using R and Stata.
This book provides statisticians with an understanding of the critical challenges currently encountered in oncology trials. The book covers state-of-the-art approaches to the design and analysis of cancer clinical trials, such as adaptive designs, biomarker-based trials, and dynamic treatment regimes.
The proposed book will focus on practical issues in pharmaceutical/clinical research and development from both regulatory and scientific perspectives. The book will outline and clarify those issues that have been commonly misused in the subject area of regulatory science.
This book is a concepts-based introduction to statistical procedures that prepares public health, medical, and life sciences students to conduct and evaluate research. Thoroughly revised, this third edition includes a new chapter introducing the basic principles of Study Design.