The diagnosis of myelodysplastic syndromes (MDS), a heterogeneous group of clonal hematopoietic disorders, is being made with increasing frequency over the past decade owing to increased recognition, improved understanding, and an aging population.

Infections are among the most frequent complications in patients with hematological malignancies and in those undergoing high-dose chemotherapy and autologous hematopoietic stem cell transplantation.

This handbook continues to provide the core knowledge needed in clinical practice for the diagnosis and management of patients with disorders of the blood. Major advances in the specialty have been reflected in this thoroughly revised new edition. Differential diagnoses, relevant investigations and management guidelines are covered.