Edward P. Sarafino's "Health Psychology: Biopsychosocial Interactions, 6e" integrates research and theory from many disciplines - such as, psychology, sociology, medicine, allied health, and health and physical education - to describe the interconnectedness between psychology and health. The psychological research cited in the text reflects an eclectic orientation and supports a variety of behavioral, physiological, cognitive, and social/personality viewpoints.

Sarafino integrates a focus on lifespan development in health and illness throughout the text. Emphasis is also placed on health and prevention while integrating gender, ethnic, and age differences and similarities. In addition, the book has an internationalized content, giving health information from 14 countries around the world.